Aesthetics over function? Naw - it's not an Apple product after all.
The goofy aesthetics of the Pandora are, frankly, part of it's charm.
The inner lip of the screen section that makes a 'hood' around the edge serves several functions. It keeps the lid up and off of the keyboard & game controls. It allows those controls to stand UP from the base instead of having to be recessed - which would be a usability nightmare. That lip also gives just a little bit of shade needed in bright environments to cut down on screen glare.
The lip on the screen also allows (in theory) for the lid to truly close tight to the base. The reality is that there really is a fitment issue such that it only touches the bottom case plastic in the front-middle and gaps a bit on the right and a lot on the left. I suspect this is part of the Pandora's mold history and how many times it had to be 'tweaked' has resulted in what is more or less a hand-carved mold set. I fully expect it's successor to have a lid that closes flat to the base.
Having the ABXY game keys engraved instead of printing means that the letters will never wear off. Could they have been printed and gel capped instead of individual plastic pieces - maybe, but the feel would be all wrong. Again, use/function trumps aesthetics.
Exposed speaker grills aren't a detriment - they're a bonus. It enables the speakers to be (relative to size) louder and more clear than they would be tucked behind a slit.
The glossy caps on the buttons... I could live with normal keys IF they're pretty much impervious to wear. I don't know how many desktop keyboards I've worn the print off of. Those gel glossy caps on the Pandora though, they're very durable AND have a just-slightly-grip-rubbery feel to them. That sounds bad, but in the end it's good - as that slightly gripping dome can be thumb-typed on somewhat off-center and still give a positive feel from the key presses AND makes it easy to 'count keys' passing under the thumbs to the point of essentially touch-thumb-typing. Could this be done better? We're about to find out on the Pyra. Can it be prettier? Maybe - but I don't think I care much about that. Just keep the usability standard VERY high.
I also prefer the circular D pad. It allows easier access to the diagonals - up&right for example.
I don't mind giving a nod to aesthetics, but I'm not going to give up one ounce of function to it. It isn't a DS - and never should be.