I keep managing to resist picking up a MiST board. (For one, I've already got the Firebee board which is pretty nifty (but not for gaming, more for Atari TOS as a computer, with ethernet etc). But on the other .. a Pandora will do the job pertty well (or RetroPie on a raspberry-pi say.)
I ran a few threads a year or two back .. the only real problem we have with Pandora as a game console is that many/most of the emu ports are Pandora-specific; contrast notaz Picodrive, or Hatari, where you configure inputs (so can work with gamepads etc), versus most emus where they assume Pandora keyboard and controls. As such, we do have Atari ST and SMS/Genesis for example that can run on Pandora TV-out, and use gamepads or usb joysticks etc (such as a classic Atari/Commodore joystick on a USB adapter). Works well. Or a raspberry pi etc of course..
So I keep waffling.. a MiST is awesome kit, and fun to hack on (fpga dev board!) and also has a couple other microciontrollers to play with; its aalso good kit for anyone to have,. But if we already have a Pandora.... we're rather covered, for all these various devices out there, right?
(Ignoring the emulation versus simulation-in-FPGA argument; that argument also leads to 'why don't you just plug your classic machine into the TV and renders this particular discussion moot.)
But damnit if I don't look at the MIST board every single month; I've got some of Lothareks gear, and its well made stuff. They also published the schematic and pcb and all source.. great guys.
jeff