I'm looking at the Pandora as a "replacement" of my PSP and my PocketPC (Axim x51v). Of course I will keep those machines too, they're both great for their own reasons. But Pandora should be able to do most of the things I use them for, and much more too.
Pandora has also affected my computer buying decisions.
I was planning to get an eeepc this summer, or something like it. But now I'm wondering if Pandora would do most of the things I would've used the eeepc for while mobile. I think it might, and it's even smaller and lighter. So in that case, I may get a full sized notebook with more storage and power instead of an eeepc (or eeepc clone) for the house. Pandora would be the road (and restroom, heh) machine.
If Pandora comes thru as a UMPC (and with 2 SD slots, Linux, touchscreen and a keyboard, it should), I think Craig and Co. may have trouble meeting demand.