It's very easy to change the layout from qwerty to dvorak using Windows or Ubuntu. I never used Angstrom before, but I don't see why it shouldn't have a setting as basic and vital as that, but the Pandora uses its own special layout so maybe just some minor adjustment for usability? I think the designers already hadve these things in mind when they were design the Pandora keyboard though.
Btw, I spent a week learning to type in dvorak, then I quited because I didn't felt it was worth it. I have never experienced cramping typing with normal keyboard layout and I'm too dumb to think more than 100 words per minutes, so no need to try and type faster than my own thoughts.
I bought dvorak stickers on amazon.com that can be pasted on each of the keyboard's keys, but the Pandora keys are going to be pretty small.