For the sake of argument, suppose the Pyragon/whatever has the following connectors arranged around the edge of the base:
I suggest:
back:-----[shoulder]--[EXT]--[uSBslave]--[Power/USBhost]--[videoOut]--[shoulder]
left:--------------------------------------[sDXC]---------------------------------------------
right:------------------------------------[sDXC]---------------------------------------------
front:----[headset]---[volumeControl]---[uSBhost]---[powerSwitch]---[holdSwitch]
Mine:
Back: --L1L2SplitRocker--Power--USB3Host--USB2.0microOTG--DualModeDPorHDMI--R1R2SplitRocker
Left: ---------RecessedVolumeWheel--RecessedPower&HoldSwitch--LanyardHole1--
Right: ------------SDXC-SDXC----------LanyardHole2--
Front: ----HeadphoneMicJack--HeadphoneModeSelector---HeatRadiatorHeatRadiator----LEDstatusBank--
Explanation:
All wired ports but headphone audio jack on the back. Simplifies docking.
Shoulder buttons are split-rocker > style meant to be run with a single finger on each side. Roll left finger up for L1, roll left finger down for L2, mash for L1+L2.
Power - Barrel is fine.
USB3Host - full sized. Yes, only one full sized USB port on the device. Let's not get greedy with board space.
USB2.0 micro OTG. This is a host/device/charging (2w max) port. It's the same one as used on most modern cell phones. Forget your charger? Pick up any micro-USB phone or tablet charger. It can be used as a USB device or host too.
Dual Mode Display Port OR HDMI. I can see doing DisplayPort, but ONLY if we can get the full dual mode signal output to enable passive adapters to DVI & HDMI. If we can't get DualMode DP, then it pretty much has to be HDMI for compatibility.
http://en.wikipedia.org/wiki/DisplayPort#Dual-mode_DisplayPort
Volume, power/hold on left. I use my Pandora as an audio player in my left shirt pocket while flying. It would be convenient to be able to put it on hold (pause/mute) and adjust the volume without removing it from the pocket. This also requires that the headphone jack be on the far left of the front edge (like Pandora). These are recessed a bit, so they aren't going to dig into your hand or get moved accidentally while you're playing games.
SDXC on the right. It's too bad nobody makes a dual-SD card stacked feature/port or these two could sit on top of each other. They can still sit side by side. The board space behind them isn't all 'wasted'. There are quite a few components that can sit behind them. Again, recessed enough to avoid conflicts with gamer's hands.
Lanyard/strap holes on left and right back corners. Removed from the back to ease docking. Put on both sides for ambidexterity.
Front left headphone/mic jack with a switch to the right of it to change the wiring from 'standard' to 'apple' for compatibility with all headphones.
About 70% of the front edge could be 'portless' and instead be a passive heat radiator. This would potentially allow the SoC to run at higher clocks longer for extended gaming.
Front right corner could house the status LEDs. Easy to check, doesn't shine in eyes during gaming.