http://gs113.photobucket.com/groups/n213/I0S2J7KION/
Browse through there, you'll find a lot of people holding the Pandora in pretty much the same way... Except for a couple with ED holding it out like a candy bar ad.
See, thing is if they are willing to redesign the board to accommodate placement of new hardware, or rearrangement of hardware, then I think there's more opportunity there. Small changes to the board would probably be realistic, but looking at what's already there, top and bottom of the board, where all the parts fit in the case, and so on, there's not really much room for much more. Of course MWeston would be able to speak on that part more, but things look really, really tight inside already.
One thing I actually wouldn't mind seeing is a reduction in height of the case, which I think might be technically possible if you're willing to lose some button height. I would imagine this could go no more than maybe 2mm or the controls would lose their feel. Could cheat other areas, too. I'm not sure how thick the speakers are, but moving them to the light pipe area could reduce the depth of the lid.
The internal SD card slot would probably work best if it were a MicroSD, since the hardware would be a lot smaller and you could fit it in more locations.
About the SD card slots having mount/unmount buttons, is there a problem with the current push in/push in again to eject method? All laptops I've had and nearly every portable SD card device I've had use this method without problems. The card sits very securely in the slot, isn't prone to accidental ejection, and is easily accessible. I'm under the impression that the Pandora's slots are no different.