CPS2 can be very processor-intensive. I use the PC version all the time, and on my parent's PC (Intel Celeron 466mhz, 128MB RAM) it kind of chugs. It runs flawlessly on my own PC (Pentium III 1ghz, 512MB RAM).
I suppose it's possible, but I don't know a lot about the GP hardware yet. CPS2 is a pretty big leap over CPS1 though.