you may know this already but:
a good chunk of the fenix games have been ported over.
many games that were ported to gp32 from pc, have been ported to gp2x as well.
xRick, another world, beats of rage, doom-heretic-hexen-quake-rott, scummvm, etc.
in some cases the authors of original gp32 games have ported them to gp2x.
electronia, perfectfit, smashGP, spout, and more i'm sure.
and some of the emulators are as good or better than the gp32 equivalents, except for battery life. from what i've heard, anyway.
but there still are a lot of apps that are gp32-exclusive, and will have to remain that way. if squidge's goals with spot are in fact reachable, and if he decides to keep working on it, then you may see something, but otherwise, the answer is, sadly, no.